Thank you for your post. In order to better assist you, can you please reach out to us via help.avenzamaps.com. It’s possible that the app is in a state that cannot be saved (this can happen when a map becomes corrupt, or data, etc.). If you can reach out to us though we can try a couple of things before an uninstall/reinstall process.
Adobe released an update to Illustrator 2021 (v25.3) that includes native support for M1 Devices and Rotate Artboard functionality. Please note these features are not yet supported within MAPublisher at this time. See compatibility notes.